Humans have been oblivious to the fact that dogs have been fighting for thousands of years to keep humankind from falling under the rule of the cats. When Mr. Tinkles (voice of Sean Hayes), a rogue cat, initiates a plan to disable the world's dog population by making humans allergic to all manner of canines and thus leaving humans defenseless against feline tyranny, a team of super secret agent dogs and a puppy named Lou (voice of Tobey Maguire) come to the rescue and save humans from slavery. Also with Jeff Goldblum, Elizabeth Perkins, Alexander Pollock, Alec Baldwin, Michael Clarke Duncan, Joe Pantoliano and Susan Sarandon. [1:33]

SEX/NUDITY 0 - A couple of hugs. Some flirtations and references to two dogs having had a romantic relationship.

VIOLENCE/GORE 4 - A dog is pulled out of a burning building and appears to be dead. A cat throws a bomb that explodes and sends spikes flying, nearly hitting dogs and tearing up a house. A cat throws knives at dogs. A dog catches a boomerang knife mid-air and flies through the air, landing on a cat. A cat picks a dog up into the air with a vehicle that has a huge, mechanical claw. A dog and a ninja cat fight with karate kicks and punches; the dog ends up being thrown through the air, he knocks over a garbage can and is covered with trash. A dog throws a cat into a wall where he is smashed behind a door (we see him flattened). A cat is sprayed with flocking (fake snow) liquid and is splattered against a window. Three people are tied to chairs in a burning office. A dog bone explodes, nearly blowing up a dog. A factory explodes with sparks flying, windows crashing and the building bursts open. A woman hits a dog with a broom. A dog is surrounded by cats who presumably attack him: we see the dog later, covered with a fishing net and whimpering. A dog runs into a closed window face first and slides down leaving a streak of slobber, and a dog tries to catapult himself through a window but falls short, crashing into a window ledge and falling hard on the ground. A cat is catapulted from a tree and flies through an open kitchen window knocking a woman down to the floor, and a cat slams into the divider window in a limousine. A woman in a car nearly hits a cat. We see a cat lying still in the street (we assume she has been hit by a car, but she is pretending). A cat holding a big knife yells at another cat. A woman punches a comatose man hard in the chest to start his heart. We see a big, dark, creepy looking house while ominous music plays in the background. A bucket falls on a dog's head. A man grows blisters on his face and hands (it's an allergic reaction). A man holds a gun-like device and he injects himself in the arm. A group of ninja cats hang from flying machines, are dropped and open parachutes -- they also wear green night-vision goggles. There's a chase between a cat and a dog; the dog knocks down two people carrying groceries and eventually runs head-first into a tree. A dog dangles from a tree limb trying to reach a cat and the cat scratches him causing him to fall. A dog dangles from a cabinet which nearly falls on top of him. A dog jumps through an open kitchen window knocking a woman down to the floor. A dog jumps from a window and dangles from a vehicle with a mechanical claw. We see a man in a bed connected to a bunch of tubes and monitors. A smoke bomb is shot into a car and it puts the occupants to sleep. A cat is tied to a chair and a dog is taken away in a van full of cats. A man licks a dog's nose and sniffs his fur. A cat coughs up a couple of huge fur balls that turn out to be weapons. Some cats drive a car recklessly, nearly hitting people and sending things flying, and dogs drive a rocket-car through a tunnel really fast. A huge number of vials are broken when a soccer ball bounces into a laboratory, and a cork is shot from a gun and it bounces around an office breaking things and starting a fire. Two women scream when a cat talks to them. A group of dogs drink from toilets, a cat blows a drug into a boy's face, a stuffed cat explodes, a dog flatulates, and a cat plants some dog feces on a carpet.

LANGUAGE 3 - 1 scatological term, 1 mild profanity, some name-calling, several non-obscene scatological terms, allusions to an animal's private parts, some insults and 5 religious exclamations.

DISCUSSION TOPICS - Being lonely, homeless dogs, parental preoccupations, greed, taking over the world, power, cats.

MESSAGE - An adventurous life can be a lonely one. Everybody needs a family.